In a large mixing bowl, add the chicken tenders and buttermilk. Use kitchen tongs to turn the chicken and cover all sides, then let it sit for 15 minutes.
Meanwhile, in a pie pan or shallow baking dish, add the breadcrumbs, Parmesan cheese, garlic powder, onion powder, dry mustard, paprika, salt, and pepper. Mix well.
Using tongs, remove the chicken tenders one at a time, allowing excess buttermilk to drip off. Place the chicken tender into the breadcrumb mixture and coat on all sides, pressing gently.